An FDA advisory panel has “soundly rejected a plan” to offer Pfizer COVID-19 vaccine booster shots to most Americans in what represents a major blow to the multinational pharmaceutical company that saw profits soar through the COVID-19 pandemic.

The vote, held earlier today, was 16-2 against advising COVID-19 booster shots for Americans. Per the Associated Press, this also represents “a blow to the Biden administration’s” mass vaccination efforts.

“Members of the Food and Drug Administration panel of outside efforts voiced frustration that Pfizer had provided little data on safety of extra doses,” the report explained. They also “complained that data provided by the Israeli researchers about their booster campaign might not be suitable for predicting the U.S. experience.”